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Oxidative Stress 1

Oxidative Stress

What it is and how to counteract it

Oxidative stress

What is it?

It is the situation of imbalance between the production of waste substances (free radicals) and the ability of our body (antioxidants) to neutralize them. It is not a true disease but a condition of discomfort that favors the onset of diseases in the medium-to-long term. This can happen either due to excessive production of reactive species, a deficiency of antioxidants, or both causes.

Free radicals are dangerous substances when the antioxidant system fails to neutralize them, because they attach to cell molecules and can cause various diseases, including the so-called premature aging.

There are primary and secondary defenses that work in synergy to block reactive oxidizing species. This balance is defined by researchers as “homeostasis.” The primary defenses are the enzymatic systems, genetically predetermined as they depend on DNA. Secondary defenses, on the other hand, are found in the blood, and it is through specialized tests that it is possible to quantify them and provide a detailed report on their quality.

Oxidative Stress 1
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What does oxidative stress

Among the main "exogenous" factors affecting the organism, the following play an important role:

  • • Incorrect diet;
  • • Sedentary lifestyle;
  • • Alcohol abuse;
  • • Drug use;
  • • Smoking;
  • • Chronic diseases;
  • • Medications;
  • • Environmental pollution;
  • • Excessive physical and mental stress;
  • • Excessive exposure to solar radiation.
Oxidative Stress 1
Oxidative Stress 1
Oxidative stress

The damages

An oxidative stress condition has been shown to be correlated with the damage induced by the most common chronic-degenerative diseases, as well as pathological aging. Furthermore, among the list of pathological conditions related to oxidative stress, are those known as "Noncommunicable Diseases" (NCDs), which we have learned are the main and most deadly killers we know:

  • • Myocardial infarction;
  • • Cerebral strokes;
  • • Diabetes mellitus;
  • • Chronic respiratory diseases;
  • • Cancer.
Oxidative Stress 1
Oxidative stress

How to counteract

The first step is to analyze the current state and determine whether or not there is an oxidative balance situation. In Lucia Magnani's laboratory, dedicated to this type of investigation, numerous parameters—both plasmatic and cellular—are measured using special equipment and highly advanced techniques. Combined with metabolic-type analyses, these provide a comprehensive overview of the situation.
The second step is to correct any imbalance through:

  • • Improvement of lifestyle;
  • • Healthy diet rich in antioxidants;
  • • Physical activity appropriate for type, intensity, and frequency;
  • • Intake of specific dietary supplements.


The results of these tests help the medical staff to create a "tailor-made" prevention program, to restore balance (homeostasis), correct bad habits, and transfer healthy exercises and practices, values, and knowledge that will contribute to creating a wellness experience that will be the launchpad for a new lifestyle.

Oxidative Stress 1
Oxidative Stress 1
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